Genetic Code and Silent Mutations

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The table shows the mRNA codons for three amino acids.

Valine Threonine Proline
GUU ACU CCU
GCC ACC CCC
GCA ACA CGA
GCG ACG CCG

Which substitution mutation of a base triplet on a DNA strand will lead to the same polypeptide being formed at translation?

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Hint

Remember that the DNA strand provided is likely the template (non-coding) strand. Transcribe the DNA triplets into mRNA codons using base pairing rules (A pairs with U, T pairs with A, C pairs with G, G pairs with C) and then use the table to see which mutation results in the same amino acid.

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Complete Answer

GCT to GGA

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